Diet-quality scores and the risk of type 2 diabetes in men.
Diet-quality scores and the risk of type 2 diabetes in men.
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饮食质量分数和男性2型糖尿病的风险。
DOI：
10.2337/dc10-2352
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发表时间：
2011-05
期刊：
影响因子：
16.2
通讯作者：
Hu FB
中科院分区：
文献类型：
--
作者：
de Koning L;Chiuve SE;Fung TT;Willett WC;Rimm EB;Hu FB
1）比较与心血管疾病呈负相关的饮食质量评分与2型糖尿病发病率的相关性，2）检验不同阶层绝对风险降低的差异。来自卫生专业人员随访研究的男性，最初没有2型糖尿病，心血管疾病或癌症（n = 41，615），随访≤20年。健康饮食指数（HEI）2005年，替代HEI（aHEI）推荐食物评分，替代地中海饮食（aMED）评分和饮食方法停止高血压（DASH）评分计算食物频率问卷。采用含时变协变量的考克斯比例风险模型，按五分位数和连续间隔评估风险。有2，795例2型糖尿病病例。多变量校正后，aHEI、aMED和DASH评分与风险降低显著相关。1-SD增加与9-13%的风险降低相关（P < 0.01），DASH评分与独立于其他评分的较低风险相关。与正常体重者相比，这些评分与超重或肥胖者的绝对风险较低相关（交互作用P < 0.01）。几个饮食质量评分与2型糖尿病的风险较低有关，反映了一种常见的饮食模式，其特征是高摄入植物性食物，如全谷物;适度饮酒;低摄入红肉和加工肉类，钠，含糖饮料和反式脂肪。高质量的饮食可能会在糖尿病病例中产生最大的减少，其次是那些具有高BMI的人。
To 1) compare associations of diet-quality scores, which were inversely associated with cardiovascular disease, with incident type 2 diabetes and 2) test for differences in absolute-risk reduction across various strata. Men from the Health Professionals Follow-Up Study, who were initially free of type 2 diabetes, cardiovascular disease, or cancer (n = 41,615), were followed for ≤20 years. The Healthy Eating Index (HEI) 2005, the alternative HEI (aHEI) the Recommended Food Score, the alternative Mediterranean Diet (aMED) Score, and the Dietary Approaches to Stop Hypertension (DASH) Score were calculated from food-frequency questionnaires. Cox proportional hazard models with time-varying covariates were used to assess risk by quintiles and continuous intervals. There were 2,795 incident cases of type 2 diabetes. After multivariate adjustment, the aHEI, aMED, and DASH scores were significantly associated with reduced risk. A 1-SD increase was associated with 9–13% reduced risk (P < 0.01), and the DASH score was associated with lower risk independent of other scores. These scores were associated with lower absolute risk among those who were overweight or obese compared with normal weight (P for interaction < 0.01). Several diet-quality scores were associated with a lower risk of type 2 diabetes and reflect a common dietary pattern characterized by high intakes of plant-based foods such as whole grains; moderate alcohol; and low intakes of red and processed meat, sodium, sugar-sweetened beverages, and trans fat. High-quality diets may yield the greatest reduction in diabetes cases when followed by those with a high BMI.