RECENT PROGRESS IN RESEARCH ON THE NEUROPHYSIOLOGIC BASIS OF MORPHINE ADDICTION

RECENT PROGRESS IN RESEARCH ON THE NEUROPHYSIOLOGIC BASIS OF MORPHINE ADDICTION
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DOI:
10.1176/ajp.105.5.329
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发表时间:
1948-01-01
影响因子:
17.7
通讯作者:
WIKLER, A
WIKLER, A
中科院分区:
医学1区
文献类型:
--
作者:
WIKLER, A

文献摘要

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本文的目的有两个:总结了近年来在肯塔基州列克星敦的美国公共卫生服务医院神经生理实验室获得的一些实验数据,并将这些信息与来自人类吗啡成瘾精神病学研究的临床印象相结合。这样的介绍有助于将神经生理学技术对动物的研究结果置于他们的研究中。正确的角度来理解人类的精神问题。相反,这种方法说明了如何通过神经生理学技术来有利地研究一些精神问题。特别是将考虑吗啡2成瘾对“实验性神经病”的完整犬、慢性去皮质犬和慢性脊髓犬的影响。某些其他药物的实验也将被描述,因为它们与吗啡成瘾问题有关。
This paper was prepared with the dual purpose in mind of summarizing some of the experimental data acquired in recent years in the neurophysiological laboratory of the US Public Health Service Hospital at Lexington, Kentucky, and integrating this information with clinical impressions derived from psychiatric studies of morphine addiction in man. Such a presentation aids in placing the results of investigations on animals with neurophysiological techniques in their proper perspective with regard to the understanding of psychiatric problems in man. Conversely, this method illustrates how some psychiatric problems can be investigated with advantage by means of neurophysiological techniques. In particular will be considered the effects of morphine 2 addiction on in-tact dogs with “experimental nellrosis,” on chronic decorticated dogs, and on chronic spinal dogs. Certain experiments with other drugs will also be described because of the bearing they have on the problem of morphine addiction.