COMPUTED ULTRASOUND TOMOGRAPHY IN ECHO MODE FOR IMAGING SPEED OF SOUND USING PULSE-ECHO SONOGRAPHY: PROOF OF PRINCIPLE
COMPUTED ULTRASOUND TOMOGRAPHY IN ECHO MODE FOR IMAGING SPEED OF SOUND USING PULSE-ECHO SONOGRAPHY: PROOF OF PRINCIPLE
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DOI：
10.1016/j.ultrasmedbio.2014.05.019
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发表时间：
2015-01-01
影响因子：
2.9
通讯作者：
Frenz, Martin
中科院分区：
文献类型：
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作者：
Jaeger, Michael;Held, Gerrit;Frenz, Martin
诊断回波超声的局限性促使人们研究新的模式，以补充多模式设备中的超声。一种有希望的候选者是声成像速度，它被发现可以揭示患病组织的结构变化。透射超声断层扫描显示空间分辨的声速，但仅限于声学透明的乳房。我们提出了一种新颖的方法，可以使用经典的脉冲回波设备进行声速成像，从而促进新的临床应用以及与最先进的诊断超声的结合。使用发射波束控制以不同角度扫描组织时重建脉冲回波图像。沿不同传输方向的平均声速差异反映在局部回波相位中，从而可以对声速进行二维重建。在目前的原理验证研究中，我们描述了平均声速 0.6% 的对比度分辨率和 1 毫米（横向）x 3 毫米（轴向）的空间分辨率，适合诊断应用。 (C) 2015 年世界超声医学与生物学联合会。
The limitations of diagnostic echo ultrasound have motivated research into novel modalities that complement ultrasound in a multimodal device. One promising candidate is speed of sound imaging, which has been found to reveal structural changes in diseased tissue. Transmission ultrasound tomography shows speed of sound spatially resolved, but is limited to the acoustically transparent breast. We present a novel method by which speed-of-sound imaging is possible using classic pulse-echo equipment, facilitating new clinical applications and the combination with state-of-the art diagnostic ultrasound. Pulse-echo images are reconstructed while scanning the tissue under various angles using transmit beam steering. Differences in average sound speed along different transmit directions are reflected in the local echo phase, which allows a 2-D reconstruction of the sound speed. In the present proof-of-principle study, we describe a contrast resolution of 0.6% of average sound speed and a spatial resolution of 1 mm (laterally) x 3 mm (axially), suitable for diagnostic applications. (C) 2015 World Federation for Ultrasound in Medicine & Biology.