The gamut of human infections caused by Dematiaceous fungi.

The gamut of human infections caused by Dematiaceous fungi.
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由暗色真菌引起的一系列人类感染。

DOI:
10.3314/jjmm1960.22.1
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发表时间:
1981
期刊:
影响因子:
4.9
通讯作者:
Libero Ajello
Libero Ajello
中科院分区:
医学2区
文献类型:
--
作者:
Libero Ajello

文献摘要

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四个品种的人类感染所造成的真菌的菌丝体或分生孢子或两者都是深色的,描述和讨论的标题下,浅表,皮肤,皮下和全身真菌病。三种疾病,黑斑痣,黑色素瘤和角膜炎,被认为是在浅表类。本文分别对4种和17种病原体的临床表现、体内和体外形态学进行了简要描述。由暗色病原体引起的皮下真菌病有着色芽生菌病和暗色丝孢菌病。前者被认为是由Cladophialophora属、Cladosporium属、Fonsecaea属、Phialophora属和Rhinocladiella属的六种霉菌中的任何一种引起的。真菌被认为是暗色丝孢真菌病的病原体,目前共有32种。着色芽生菌病和暗色丝孢菌病的根本区别在于它们各自的病原体所呈现的组织形式。在着色芽生菌病中,寄生虫表现为大的、鼠状、厚壁的暗色细胞。在暗色丝孢菌病中,真菌基本上以暗壁有隔膜的菌丝成分出现。已知由6属9种霉菌引起的黑色颗粒霉菌瘤。在一定范围内,可以通过颗粒的特征推断出给定的黑色颗粒足菌肿的身份。
The four varieties of human infections caused by fungi whose mycelium or conidia or both are dark colored, are described and discussed under the headings of superficial, cutaneous, subcutaneous and systemic mycoses. Three diseases, black piedra, tinea nigra and mycotic keratitis, were considered in the superficial category. Their etiologic agents, respectively 4 and 17 in number were briefly described in terms of their clinical manifestations, in vivo and in vitro morphology. The subcutaneous mycoses with dematiaceous etiologic agents are chromoblastomycosis and phaeohyphomycosis. The former is considered to be caused by any one of six moulds classified in the genera Cladophialophora, Cladosporium, Fonsecaea, Phialophora and Rhinocladiella. The fungi incriminated as agents of phaeohyphomycosis, currently total 32. The fundamental differences between chromoblastomycosis and phaeohyphomycosis lies in the tissue form assumed by their respective etiologic agents. In chromoblastomycosis, the parasites occur as large, muriform, thick-walled dematiaceous cells. In phaeohyphomycosis the fungi basically occur as dark walled septate, hyphal elements. The mycetomas with black granules are known to be caused by 9 species of moulds classified in 6 genera. Within limits, the identity of a given black grained mycetoma can be deduced through the characteristics of the granules.