Occupation and Thyroid Cancer: A Population-Based, Case-Control Study in Connecticut
Occupation and Thyroid Cancer: A Population-Based, Case-Control Study in Connecticut
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DOI：
10.1097/jom.0000000000000637
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发表时间：
2016-03-01
影响因子：
3.2
通讯作者：
Zhang, Yawei
中科院分区：
文献类型：
--
作者：
Ba, Yue;Huang, Huang;Zhang, Yawei
目的：探讨不同职业与甲状腺癌发病风险的关系。方法：采用病例对照研究方法，对2010 - 2011年康涅狄格州462例经病理证实的甲状腺癌病例和498例对照进行研究。那些从事建筑物和地面清洁，维修职业，害虫防治，零售和客户服务的人也增加了乳头状甲状腺癌的风险。结论：肿瘤大小与甲状腺癌的发生有一定的相关性，肿瘤大小与甲状腺癌亚型有一定的特异性。
Objective:The study aims to explore the associations between various occupations and thyroid cancer risk.Methods:A population-based, case-control study involving 462 histologically confirmed incident cases and 498 controls was conducted in Connecticut in 2010 to 2011.Results:A significantly increased risk of thyroid cancer, particularly papillary microcarcinoma, was observed for those working as the health care practitioners and technical workers, health diagnosing and treating practitioners, and registered nurses. Those working in building and grounds cleaning, maintenance occupations, pest control, retail sales, and customer service also had increased risk for papillary thyroid cancer. Subjects who worked as cooks, janitors, cleaners, and customer service representatives were at an increased risk of papillary thyroid cancer with tumor size more than 1cm.Conclusion:Certain occupations were associated with an increased risk of thyroid cancer, with some tumor size and subtype specificity.