Strength of Attentional Modulation on Cortical Auditory Evoked Responses Correlates with Speech-in-Noise Performance in Bimodal Cochlear Implant Users.
Strength of Attentional Modulation on Cortical Auditory Evoked Responses Correlates with Speech-in-Noise Performance in Bimodal Cochlear Implant Users.
复制标题
DOI：
10.1177/23312165221141143
复制
发表时间：
2022-01
影响因子：
2.7
通讯作者：
Choi, Inyong
中科院分区：
文献类型：
--
作者：
Lee, Jae-Hee;Shim, Hwan;Gantz, Bruce;Choi, Inyong
关键词：
听觉选择性注意是噪声环境下理解语音的一种重要的自上而下的认知机制。耳蜗植入体（CI）用户在噪声中的语音表现存在很大的差异，这不容易用外周听觉特征或人口统计学因素来解释。因此，有必要了解，如果听觉认知过程，如选择性注意解释这种变化。本研究通过量化注意任务中皮层听觉反应的注意调制，并将其个体差异与噪声中的语音表现进行比较，直接解决了这个问题。在我们的注意力实验中，与CI的参与者被给予一个前刺激的视觉提示，引导他们的注意力到两个语音流中的任何一个，并被要求选择一个偏离音节的目标流。两个语音流由每800 ms说五次“向上”的女声和每1 s说四次“向下”的男声组成。 每一个音节的起始都能引起不同的事件相关电位（ERP）。在每个音节开始时，计算两种注意条件（注意-忽略）之间的ERPs幅度差异。这种ERP幅度差异充当注意调制强度的代理。我们的组水平的分析表明，ERP的幅度更大时，音节被注意到比忽略，显示注意调制皮层听觉反应。此外，注意调制的强度与噪声中的语音表现有显著的相关性。这些结果表明，皮层听觉反应的注意调制可能提供了一个神经标记，用于预测CI用户在噪声中的语音听力的临床测试的成功。
Auditory selective attention is a crucial top-down cognitive mechanism for understanding speech in noise. Cochlear implant (CI) users display great variability in speech-in-noise performance that is not easily explained by peripheral auditory profile or demographic factors. Thus, it is imperative to understand if auditory cognitive processes such as selective attention explain such variability. The presented study directly addressed this question by quantifying attentional modulation of cortical auditory responses during an attention task and comparing its individual differences with speech-in-noise performance. In our attention experiment, participants with CI were given a pre-stimulus visual cue that directed their attention to either of two speech streams and were asked to select a deviant syllable in the target stream. The two speech streams consisted of the female voice saying “Up” five times every 800 ms and the male voice saying “Down” four times every 1 s. The onset of each syllable elicited distinct event-related potentials (ERPs). At each syllable onset, the difference in the amplitudes of ERPs between the two attentional conditions (attended - ignored) was computed. This ERP amplitude difference served as a proxy for attentional modulation strength. Our group-level analysis showed that the amplitude of ERPs was greater when the syllable was attended than ignored, exhibiting that attention modulated cortical auditory responses. Moreover, the strength of attentional modulation showed a significant correlation with speech-in-noise performance. These results suggest that the attentional modulation of cortical auditory responses may provide a neural marker for predicting CI users’ success in clinical tests of speech-in-noise listening.
登录
查看更多内容
影响因子：
2.8
作者：
Choi, Inyong;Wang, Le;Bharadwaj, Hari;Shinn-Cunningham, Barbara
通讯作者：
Shinn-Cunningham, Barbara
影响因子：
2.4
作者：
CHERRY, EC
通讯作者：
CHERRY, EC
DOI：
10.1044/1092-4388(2001/002
发表时间：
2001-02-01
影响因子：
2.6
作者：
Mackersie, CL;Prida, TL;Stiles, D
通讯作者：
Stiles, D
影响因子：
2.4
作者：
Nelson, PB;Jin, SH;Nelson, DA
通讯作者：
Nelson, DA
DOI：
10.1098/rstb.1998.0281
发表时间：
1998-08-29
期刊：
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
影响因子：
--
作者：
Hillyard, SA;Vogel, EK;Luck, SJ
通讯作者：
Luck, SJ