Impact of major cardiovascular disease risk factors, particularly in combination, on 22-year mortality in women and men
Impact of major cardiovascular disease risk factors, particularly in combination, on 22-year mortality in women and men
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DOI：
10.1001/archinte.158.18.2007
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发表时间：
1998-10-12
影响因子：
--
通讯作者：
Stamler, J
中科院分区：
文献类型：
--
作者：
Lowe, LP;Greenland, P;Stamler, J
背景：目前女性心血管疾病（CVD）危险因素指南的适宜性仍在争论中。目的：通过对大量人群样本的长期随访，为女性和男性提供关于当前心血管疾病危险因素指南适宜性的新数据。方法：根据芝加哥心脏协会工业检测项目的现行临床指南，确定8686名女性和10503名男性的心血管疾病危险因素状况及其对死亡率的长期影响；平均随访时间为22年。结果：在基线时，只有6.6%的女性和4.8%的男性在所有3个主要危险因素(胆固醇水平、
Background: The appropriateness of current cardiovascular disease (CVD) risk factor guidelines in women continues to be debated.Objective: To present new data on the appropriateness of current CVD risk factor guidelines, for women and men, from long-term follow-up of a large population sample.Methods: Cardiovascular disease risk factor status according to current clinical guidelines and long-term impact on mortality were determined in 8686 women and 10 503 men aged 40 to 64 years at baseline from the Chicago Heart Association Detection Project in Industry; average follow-up was 22 years.Results: At baseline, only 6.6% of women and 4.8% of men had desirable levels for all 3 major risk factors (cholesterol level,