A focal mass-forming autoimmune pancreatitis mimicking pancreatic cancer with obstruction of the main pancreatic duct.
A focal mass-forming autoimmune pancreatitis mimicking pancreatic cancer with obstruction of the main pancreatic duct.
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DOI：
10.1007/s11605-011-1543-5
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发表时间：
2011-12
期刊：
影响因子：
--
通讯作者：
Ku Y
中科院分区：
文献类型：
--
作者：
Matsumoto I;Shinzeki M;Toyama H;Asari S;Goto T;Yamada I;Ajiki T;Fukumoto T;Ku Y
自身免疫性胰腺炎（AIP）是一种罕见的疾病，其表现与胰腺癌（PC）非常相似。对于临床医生来说，区分它们是非常重要的，因为它们的治疗和预后有很大的不同。典型的影像学表现，特别是内镜逆行胰胆管造影（ERCP）观察到主胰管（MPD）弥漫性或节段性狭窄，壁不规则，是诊断AIP的必要条件。另一方面，MPD阻塞是ERCP最常见的特征之一。我们报告一例罕见的局灶性肿块性AIP患者，由于ERCP上MPD阻塞，强烈怀疑为PC。用目前的诊断方法很难区分PC和AIP。我们将继续努力区分这两种疾病，以防止不必要的手术。
Autoimmune pancreatitis (AIP) is a rare disease that closely mimics pancreatic cancer (PC) in its presentation. It is very important for clinicians to distinguish one from the other because their treatment and prognosis are vastly different. Typical radiological imaging findings, in particular observation of diffusely or segmentally narrowed main pancreatic duct (MPD) with an irregular wall by endoscopic retrograde cholangiopancreatography (ERCP), are essential for making the diagnosis of AIP. On the other hand, MPD obstruction is one of the most frequent features on ERCP. We report a rare case of a patient with focal mass-forming AIP strongly suspected of being PC because of MPD obstruction on ERCP. It was difficult to distinguish PC from AIP with current diagnostic modalities. We will continue to make an effort to distinguish between the two disorders to prevent unnecessary surgery.