CSF Albumin: Albumin CSF/Serum Ratio (Marker for Blood-CSF Barrier Function)
CSF Albumin: Albumin CSF/Serum Ratio (Marker for Blood-CSF Barrier Function)
复制标题
脑脊液白蛋白：脑脊液白蛋白/血清比率（血液-脑脊液屏障功能的标志物）
DOI：
10.1007/978-3-319-01225-4_9
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
H. Hegen
中科院分区：
文献类型：
--
作者：
H. Tumani;H. Hegen
CSF白蛋白是评价血-CSF屏障通透性的理想参数。CSF/血清白蛋白比值（Q-Alb）用于校正个体血液白蛋白浓度，Q-Alb异常升高发生在各种疾病中，包括炎性和非炎性神经系统疾病。轻度至中度Q-Alb升高是糖尿病和免疫介导的多发性神经病或病毒性脑膜炎的典型症状，而中度至重度Q-Alb升高与CNS感染、免疫介导的多发性神经根炎或重度椎管狭窄相关。
CSF albumin serves as an ideal parameter to evaluate the permeability of the blood-CSF barrier. The CSF/serum albumin ratio (Q-Alb) has to be used in order to correct for the individual blood concentration of albumin.Abnormal elevations of Q-Alb occur in various disorders including inflammatory and noninflammatory neurological diseases. Mild-to-moderate elevations of Q-Alb are typical for diabetic and immune-mediated polyneuropathies or viral meningitis, while moderate-to-severe Q-Alb elevations are associated with CNS infections, immune-mediated polyradiculitis or severe spinal canal stenosis.