Allelochemicals targeted to balance competing selections in African agroecosystems
Allelochemicals targeted to balance competing selections in African agroecosystems
复制标题
旨在平衡非洲农业生态系统竞争选择的化感化学物质
DOI：
10.1038/s41477-019-0563-0
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发表时间：
2019-12-01
期刊：
影响因子：
18
通讯作者：
Li, Xianran
中科院分区：
文献类型：
--
作者：
Wu, Yuye;Guo, Tingting;Li, Xianran
在作为主食驯化的主要谷物中，只有高粱在谷物中具有高比例的浓缩单宁的品种，其可以通过与2型味觉受体（TAS2R）结合来触发动物的苦味感知。在这里，我们报告完成了一对重复的隐性基因（单宁1和单宁2）的单宁存在下的发现。每个基因的三个功能丧失等位基因在非单宁高粱中被鉴定为可口的食物。浓缩的单宁有效地阻止了麻雀吃高粱。单宁高粱和Quelea quelea之间的平行地理分布支持单宁在对抗这种主要食草动物威胁中的作用。人类TAS2R变异体和单宁高粱在非洲的地理分布之间的关联表明，不同的原因可能驱动了这种双向选择，根据不同的当地食草动物的威胁和人类的味觉敏感性。我们的研究揭示了人类，植物和环境之间的协同进化联系的化感物质。
Among major cereals domesticated as staple food, only sorghum has a high proportion of cultivars with condensed tannins in grain, which can trigger bitter taste perception in animals by binding to type 2 taste receptors (TAS2Rs). Here, we report the completion of uncovering of a pair of duplicate recessive genes (Tanninl and Tannin2) underlying tannin presence. Three loss-of-function alleles from each gene were identified in non-tannin sorghum desired as palatable food. Condensed tannins effectively prevented sparrows from consuming sorghum grain. Parallel geographic distributions between tannin sorghum and Quelea quelea supported the role of tannins in fighting against this major herbivore threat. Association between geographic distributions of human TAS2R variants and tannin sorghum across Africa suggested that different causes had probably driven this bidirectional selection according to varied local herbivore threats and human taste sensitivity. Our investigation uncovered coevolution among humans, plants and environments linked by allelochemicals.