Challenges of CAR- and TCR-T cell-based therapy for chronic infections
Challenges of CAR- and TCR-T cell-based therapy for chronic infections
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DOI:
10.1084/jem.20191663
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发表时间:
2020-05-01
影响因子:
15.3
通讯作者:
Tan, Anthony Tanoto
中科院分区:
文献类型:
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作者:
Bertoletti, Antonio;Tan, Anthony Tanoto
While therapy with T cells engineered with a chimeric antigen receptor (CAR) or a classical T cell receptor (TCR) is revolutionizing cancer treatment, its adoption in infectious diseases has been met with considerable resistance. Can we find its value for the cure of infections?