Spatial working memory is preserved in rats treated with anabolic-androgenic steroids.
Spatial working memory is preserved in rats treated with anabolic-androgenic steroids.
复制标题
用合成代谢雄激素类固醇治疗的大鼠保留了空间工作记忆。
DOI：
10.1016/0006-8993(96)00932-8
复制
发表时间：
1996
期刊：
影响因子：
2.9
通讯作者：
Clark,AS
中科院分区：
文献类型：
--
作者：
Smith,ST;Stackman,RW;Clark,AS
研究了合成代谢雄激素类固醇（AAS）化合物对雄性大鼠空间工作记忆的影响。在一个延迟的非匹配样本的径向臂迷宫任务中，高剂量的三种单独的AAS化合物（17α-甲基睾酮、甲雄烯酮或甲磺酸睾酮）给药30天，对空间记忆或动机没有影响。在人类滥用范围内给药这些AAS化合物不会损害大鼠的空间工作记忆。
The effects of anabolic-androgenic steroid (AAS) compounds on spatial working memory were evaluated in male rats. Thirty days of administration of a high dose of three individual AAS compounds (17α-methyltestosterone, methandrostenolone, or testosterone cypionate) had no effects on spatial memory or motivation as tested on a delayed non-match-to-sample radial arm maze task. Administration of these AAS compounds at doses within the human abuse range does not impair spatial working memory in rats.