Physical activity, body mass index, and ovulatory disorder infertility
Physical activity, body mass index, and ovulatory disorder infertility
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DOI：
10.1097/00001648-200203000-00013
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发表时间：
2002-03-01
期刊：
影响因子：
5.4
通讯作者：
Manson, JE
中科院分区：
文献类型：
--
作者：
Rich-Edwards, JW;Speigelman, D;Manson, JE
很少有研究调查美国妇女典型的活动和肥胖水平是否会影响她们患排卵障碍性不孕症的风险，也没有研究分别调查中等强度和剧烈强度的运动。我们在护士健康研究II中调查了这些相关性，比较了830例排卵性不孕症和26,125例妊娠的肥胖和活动的前瞻性收集数据。我们观察到体重指数（BMI）与排卵性不孕症的相对风险之间呈U型相关，BMI低于20.0或高于24.0 kg/m2的风险增加（2）。根据美国妇女的BMI分布，这些发现表明，美国12%（95%置信区间= 7-20%）的排卵性不孕症可能归因于体重不足（BMI
Few studies have examined whether activity and adiposity levels typical of American women affect their risk of ovulatory disorder infertility, and none has examined moderate and vigorous intensity exercise separately. We investigated these associations in the Nurses' Health Study II, comparing prospectively collected data on adiposity and activity for 830 cases of incident ovulatory infertility and 26,125 pregnancies. We observed a U-shaped association between body mass index (BMI) and relative risk of ovulatory infertility, with increased risk for BMI below 20.0 or above 24.0 kg/m(2). On the basis of the BMI distribution of U.S. women, these findings suggest that 12% (95% confidence interval = 7-20%) of ovulatory infertility in the U.S. may be attributable to underweight (BMI