Gold nanoparticle decoration of DNA on silicon
Gold nanoparticle decoration of DNA on silicon
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DOI：
10.1021/la0515367
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发表时间：
2005-11-08
期刊：
影响因子：
3.9
通讯作者：
Reich, NO
中科院分区：
文献类型：
--
作者：
Braun, G;Inagaki, K;Reich, NO
阳离子纳米粒子静电组装到带负电的双链 DNA 主链上已被证明可以产生一维链，具有作为纳米电子元件的潜在用途。在本文中，使用在氨基硅烷和六甲基二硅氮烷修饰的硅表面上拉伸的微米长 DNA 模板来组装用阳离子硫代胆碱钝化的 3.5 nm 金纳米颗粒。原子力显微镜用于分析类似 5 nm 高结构的密度和缺陷，并比较带正电和中性表面。这两种表面化学物质都促进了纳米颗粒的低背景吸附，而中性表面则产生更密集的组装。
Electrostatic assembly of cationic nanoparticles onto the negatively charged backbone of double-stranded DNA has been shown to produce one-dimensional chains with potential use as nanoelectronic components. In this paper, micron long DNA templates stretched on aminosilane- and hexamethyldisilazane-modified silicon surfaces are used to assemble 3.5 nm gold nanoparticles passivated with cationic thiocholine. Atomic force microscopy is used to analyze the density and defects along the similar to 5 nm high structures, with comparison between positively charged and neutral surfaces. Low background adsorption of nanoparticles is facilitated by both these surface chemistries, while the neutral surface yields a more densely packed assembly.