Short- and long-term changes in myocardial function, morphology, edema, and infarct mass after ST-segment elevation myocardial infarction evaluated by serial magnetic resonance imaging
Short- and long-term changes in myocardial function, morphology, edema, and infarct mass after ST-segment elevation myocardial infarction evaluated by serial magnetic resonance imaging
复制标题
DOI：
10.1016/j.ahj.2007.06.038
复制
发表时间：
2007-11-01
影响因子：
4.8
通讯作者：
Kastrup, Jens
中科院分区：
文献类型：
--
作者：
Ripa, Rasmus Sejersten;Nilsson, Jens Christian;Kastrup, Jens
背景ST段抬高型心肌梗死（STEMI）按照指南治疗后的自然病程的知识是有限的，因为STEMI后没有进行左心室收缩功能、水肿、灌注和梗死面积的全面系列磁共振成像（MRI）。本研究的目的是评估STEMI治疗对左心室功能和灌注的影响，并验证MRI心肌灌注预测左心室功能恢复的假设。对58例STEMI患者在直接经皮冠状动脉支架植入术成功后第2天、1个月和6个月进行了增强和延迟增强成像。射血分数第1个月增加6.3%（P <0.001），1 ~ 6个月增加1.9%（P
Background Knowledge of the natural course after an ST-elevation myocardial infarction (STEMI) treated according to guidelines is limited because comprehensive serial magnetic resonance imaging (MRI) of systolic left ventricular function, edema, perfusion, and infarct size after STEMI has not been undertaken. The aim of this study was to evaluate effects of therapy for STEMI on left ventricular function and perfusion and to test the hypothesis that myocardial perfusion by MRI predicts recovery of left ventricular function.Methods One MRI, edema, first-pass perfusion, and late enhancement imaging were performed in 58 patients at day 2 and at 1 and 6 months after successful primary percutaneous coronary stent intervention for STEMI.Results Ejection fraction increased 6.3% during the first month (P < .001) and 1.9% from 1 to 6 months (P