Conversion of long-chain unsaturated fatty acids to hydroxy acids by human intestinal bacteria.
Conversion of long-chain unsaturated fatty acids to hydroxy acids by human intestinal bacteria.
复制标题
人类肠道细菌将长链不饱和脂肪酸转化为羟基酸。
DOI：
10.1099/00222615-7-2-265
复制
发表时间：
1974
影响因子：
3
通讯作者：
B. Drasar
中科院分区：
文献类型：
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作者：
J. R. Pearson;H. Wiggins;B. Drasar
概括
对来自人类粪便的 207 株细菌进行了筛选，以确定它们在体外将油酸转化为羟基硬脂酸的能力。九十四株菌株能够进行这种反应。除一种测试的肠球菌外，所有肠球菌均具有活性，并且在拟杆菌属菌株（18％）、双歧杆菌（32％）、梭菌（50％）和肠杆菌（21％）中也发现了一些活性菌株。油酸水合细菌也能够水合棕榈油酸，但不能水合亚油酸。无法证明粪便羟基硬脂酸水平与粪便中能够产生这种酸的细菌数量之间的关系。
SUMMARY
Two hundred and seven strains of bacteria from human faeces were screened for their ability to convert oleic acid to hydroxystearic acid in vitro. Ninety-four strains were able to perform this reaction. All but one of the enterococci tested were active, and some active strains were also found among Bacteroides strains (18%), bifidobacteria (32%), clostridia (50%), and enterobacteria (21%). Oleic acid-hydrating bacteria were also able to hydrate palmitoleic but not linoleic acid. Relationship could not be demonstrated between faecal hydroxystearic acid level and the number of bacteria in the faeces able to produce this acid.
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