CENTRAL SEROUS CHORIORETINOPATHY IN ENDOGENOUS HYPERCORTISOLISM
CENTRAL SEROUS CHORIORETINOPATHY IN ENDOGENOUS HYPERCORTISOLISM
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DOI：
10.1001/archopht.1993.01090090081024
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发表时间：
1993-09-01
影响因子：
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通讯作者：
KAISERKUPFER, MI
中科院分区：
文献类型：
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作者：
BOUZAS, EA;SCOTT, MH;KAISERKUPFER, MI
目的：研究中心性浆液性脉络膜视网膜病变与内源性皮质醇增多症（库欣综合征）的潜在关联。设计：对连续入院的内源性库欣综合征患者进行眼科调查。设定：一个眼科诊所的一个研究中心（国家眼科研究所，贝塞斯达，马里兰州）。患者：60例连续确诊的内源性库欣综合征。主要结果措施：结果从完整的眼科evaluation.Results：三（5%）的60例患者有一个或多个发作的适当记录的中心性浆液性脉络膜视网膜病变。在所有的情况下，发作期间发生的皮质醇hypercorticosolis.Conclusions：中心性浆液性脉络膜视网膜病变是一种罕见的表现内源性库欣综合征。由于中心性浆液性脉络膜视网膜病变与其他皮质激素过多状态有关，我们认为糖皮质激素可能在这种疾病的发展中发挥作用。
Objective: To examine the potential association of central serous chorioretinopathy with endogenous hypercortisolism (Cushing's syndrome).Designs: Ophthalmologic survey of consecutively admitted patients with endogenous Cushing's syndrome. Setting: An eye clinic of a research center (National Eye Institute, Bethesda, Md).Patients: Sixty consecutive patients with confirmed endogenous Cushing's syndrome.Main Outcome Measures: Findings from complete ophthalmologic evaluation.Results: Three (5%) of 60 patients had one or more episodes of appropriately documented central serous chorioretinopathy. In all cases, the episodes occurred during the period of hypercortisolism.Conclusions: Central serous chorioretinopathy is an uncommon manifestation of endogenous Cushing's syndrome. Since central serous chorioretinopathy has been associated with other hypercortisolemic states, we suggest that glucocorticoids may play a role in the development of this disease.