Diamond-based electrochemical aptasensor realizing a femtomolar detection limit of bisphenol A
Diamond-based electrochemical aptasensor realizing a femtomolar detection limit of bisphenol A
复制标题
金刚石基电化学适体传感器实现双酚A的飞摩尔检测限
DOI：
10.1016/j.bios.2017.01.041
复制
发表时间：
2017
影响因子：
12.6
通讯作者：
Li Hongdong
中科院分区：
文献类型：
--
作者：
Ma Yibo;Liu Junsong;Li Hongdong
In this study, we designed and fabricated an electrochemical impedance aptasensor based on Au nanoparticles (Au-NPs) coated boron-doped diamond (BDD) modified with aptamers, and 6-mercapto-1-hexanol (MCH) for the detection of bisphenol A (BPA). The constructed BPA aptasensor exhibits good linearity from 1.0×10–14to 1.0×10−9mol L−1. The detection limitation of 7.2×10–15mol L−1was achieved, which can be attributed to the synergistic effect of combining BDD with Au-NPs, aptamers, and MCH. The examine results of BPA traces in Tris-HCl buffer and in milk, UV spectra of aptamer/BPA and interference test revealed that the novel aptasensors are of high sensitivity, specificity, stability and repeatability, which could be promising in practical applications.
