Immunologic and inflammatory mediators and cognitive decline in Alzheimer's disease
Immunologic and inflammatory mediators and cognitive decline in Alzheimer's disease
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DOI：
10.1016/s0889-8561(02)00048-6
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发表时间：
2003-02-01
影响因子：
2.6
通讯作者：
Vellas, B
中科院分区：
文献类型：
--
作者：
Ahluwalia, N;Vellas, B
Local up-regulation of immune mediators is involved as a secondary or tertiary event in the development of Alzheimer's disease (AD); however, the systemic cell-mediated immune response in patients with AD may be impaired. Several factors, including malnutrition, may be involved in the reduced immune response in advanced stages of AD. A better understanding of the immune mediators that are involved in the local and systemic immune response in AD may assist in mediating the development of AD, halting its progression, and treating patients with effective anti-inflammatory drugs and immunization strategies.
