Nicotine use and its correlates in patients with psychosis
Nicotine use and its correlates in patients with psychosis
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DOI：
10.1111/j.1600-0447.2007.01085.x
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发表时间：
2007-01-01
影响因子：
6.7
通讯作者：
Lindstrom, E.
中科院分区：
文献类型：
--
作者：
Levander, S.;Eberhard, J.;Lindstrom, E.
目的：研究尼古丁的使用及其相关因素之间的精神病patients.Method：纵向自然主义研究的176例患者，诊断为精神分裂症或精神分裂症相关的精神障碍，并与利培酮治疗的研究进入。尼古丁的使用水平（吸烟，鼻烟）与其他相关的评级和测量（症状，药物治疗，副作用，体重，认知功能和结果）一起测量沿着在基线和每年一次为5 years.Results：尼古丁的使用是普通人群的两倍。只有少数尼古丁使用者是在精神病发作后开始使用的。我们找不到任何差异尼古丁用户和非用户之间的诊断，症状，副作用，体重，认知功能，个性和结果，横截面和纵向，裁决对“自我药疗”hypothes.Conclusion：一个吝啬的解释的研究结果是，患有精神病的患者不能停止尼古丁，而不是经验的使用显着的积极影响。
Objective: To examine nicotine use and its correlates among psychotic patients.Method: Longitudinal naturalistic study of 176 patients, diagnosed with schizophrenia or schizophrenia-related psychotic disorders, and treated with risperidone at study entry. Levels of nicotine use (smoking, snuffing) were measured along with other relevant ratings and measurements (symptoms, drug treatment, side effects, weight, cognitive functions and outcome) at baseline and once yearly for 5 years.Results: Nicotine use was twice as common as in the general population. Only few nicotine users had started after onset of psychoses. We could not find any differences among nicotine users and non-users in diagnosis, symptoms, side effects, weight, cognitive functions, personality and outcome, cross-sectionally and longitudinally, ruling against the 'self-medication' hypothesis.Conclusion: A parsimonious interpretation of the findings is that patients suffering from psychosis fail to desist from nicotine rather than experience significant positive effects of the usage.