Safety Considerations and Proposed Workflow for Laboratory-Scale Chemical Synthesis by Ball Milling

Safety Considerations and Proposed Workflow for Laboratory-Scale Chemical Synthesis by Ball Milling
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DOI:
10.1021/acs.oprd.2c00226
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发表时间:
2023-02-17
影响因子:
3.4
通讯作者:
Browne, Duncan L.
Browne, Duncan L.
中科院分区:
化学3区
文献类型:
--
作者:
Priestley, Ian;Battilocchio, Claudio;Browne, Duncan L.

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在球磨机中和在不存在本体反应溶剂的情况下发生的化学反应与搅拌溶液反应呈现不同的安全特性。在此,我们提出并描述了研究人员可以采取的步骤,以更好地确保他们已经考虑了一些出现的危害和措施,并最大限度地减少对自己和同事的风险。
Chemical reactions that take place in a ball mill and in the absence of a bulk reaction solvent present different safety profiles to stirred solution reactions. Herein, we present and describe steps that a researcher may take to better ensure that they have considered some of the hazards and measures that emerge and minimize the risk to themselves and their colleagues.