"Getting off the Bus Closer to Your Destination": Patients' Views about Pharmacogenetic Testing.
"Getting off the Bus Closer to Your Destination": Patients' Views about Pharmacogenetic Testing.
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DOI：
10.7812/tpp/15-046
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发表时间：
2015-01-01
影响因子：
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通讯作者：
Larson, Eric B
中科院分区：
文献类型：
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作者：
Trinidad, Susan Brown;Coffin, Tara B;Larson, Eric B
作者对处方抗抑郁药的患者进行了焦点组（试点会议加2个焦点组，n = 27）;处方卡马西平的患者（2个焦点组，n = 17）;健康患者（2个焦点组，n = 17）。虽然参与者了解药物遗传学检测的潜在优势，但许多人认为风险（歧视，污名化，医生过度依赖基因组结果，以及拒绝某些药物）可能超过了好处。这些担忧在不同的群体中都有，但在患有慢性心理健康诊断的参与者中表达得更强烈。
The authors conducted focus groups with patients prescribed antidepressants (pilot session plus 2 focus groups, n = 27); patients prescribed carbamazepine (2 focus groups, n = 17); and healthy patients (2 focus groups, n = 17). Although participants understood the potential advantages of pharmacogenetic testing, many felt that the risks (discrimination, stigmatization, physician overreliance on genomic results, and denial of certain medications) may outweigh the benefits. These concerns were shared across groups but were more strongly expressed among participants with chronic mental health diagnoses.