Mediating effect of waist:height ratio on the association between BMI and frailty: the Korean Frailty and Aging Cohort Study

Mediating effect of waist:height ratio on the association between BMI and frailty: the Korean Frailty and Aging Cohort Study
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DOI:
10.1017/s0007114519002058
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发表时间:
2020-09-14
影响因子:
3.6
通讯作者:
Park, Yongsoon
Park, Yongsoon
中科院分区:
医学3区
文献类型:
--
作者:
Kim, Minseo;Lee, Yunhwan;Park, Yongsoon

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Body weight is a major risk determinant of frailty, but the effect of obesity on frailty is controversial. The present study aimed to confirm the hypothesis that the risk of frailty is positively associated with obesity (BMI >= 30 kg/m(2)), but the association is mediated by the waist:height ratio (WHtR) in older women and men. A total of 2862 community-dwelling older individuals aged 70-84 years were assessed for frailty using the Korean version of Fatigue, Resistance, Ambulation, Illnesses, and Loss of weight index. Obesity (BMI >= 30 kg/m(2)) was associated with a higher risk of frailty compared with BMI 18.5-