Babesia (Theileria) annae in a Red Fox (Vulpes vulpes) from Prince Edward Island, Canada
Babesia (Theileria) annae in a Red Fox (Vulpes vulpes) from Prince Edward Island, Canada
复制标题
DOI：
10.7589/0090-3558-46.2.615
复制
发表时间：
2010-04-01
影响因子：
1.3
通讯作者：
Tent, Karen
中科院分区：
文献类型：
--
作者：
Clancey, Noel;Horney, Barbara;Tent, Karen
一只4-6岁雌性红狐（Vulpes Vulpes）被送到加拿大爱德华王子岛大西洋兽医学院（AVC）教学医院。在展示时，狐狸身体虚弱，粘膜苍白。进行全血细胞计数和血清生化分析。血液涂片检查发现红细胞数量少，位于中心至中心旁，单个，很少有多个，约1X2 μ m，卵圆形，形态类似微小巴贝斯虫。对全血提取的巴贝斯虫DNA进行聚合酶链反应检测和18S rRNA基因测序。结果为阳性的微巴贝虫样寄生虫遗传上相同的巴贝虫（氏巴贝虫）年。由于康复预后不佳，这只狐狸被安乐死。尸检显示多灶性到局部广泛的亚急性非化脓性脑膜脑炎，嗜酸性支气管肺炎，中度弥漫性空泡性肝病，以及与左腹部钝性创伤相关的病变。这是加拿大第一例报道的赤狐感染肾原质的病例。目前还不确定这种血液寄生虫在这只狐狸身上的存在是致病的还是偶然发现的。爱德华王子岛上巴贝斯虫物种的能力载体的潜力，这种微小巴贝斯虫样寄生虫感染其他野生和家养犬科动物的潜力，以及这种寄生虫对受感染个体健康的意义尚待确定。
A 4-6-mo-old female red fox (Vulpes vulpes) was presented to the Atlantic Veterinary College (AVC) Teaching Hospital, Prince Edward Island, Canada. On presentation, the fox was weak and had pale mucous membranes. A complete blood count and a serum biochemistry profile were performed. Blood smear examination revealed low numbers of erythrocytes containing centrally to paracentrally located, single, rarely multiple, approximately 1X2 mu m, oval to round organisms with morphology, similar to Babesia microti. Polymerase chain reaction testing and DNA sequencing of the Babesia species 18S rRNA gene were performed on DNA extracted from whole blood. Results were positive for a Babesia microti-like parasite genetically identical to Babesia (Theileria) annae. The fox was euthanized due to poor prognosis for recovery. Necropsy examination revealed multifocal to locally extensive subacute nonsuppurative meningoencephalitis, an eosinophilic bronchopneumonia, a moderate diffuse vacuolar hepatopathy, and lesions associated with blunt trauma to the left abdominal region. This is the first reported case of a red fox in Canada infected with a piroplasm. It remains uncertain whether the presence of this hemoparasite in this fox was pathogenic or an incidental finding. The potential for competent vectors of Babesia species on Prince Edward Island, the potential for this Babesia microti-like parasite to infect other wild and domestic canids, and the significance of this parasite to the health of infected individuals are yet to be determined.