Population-based survey on prevalence of adult patients with epilepsy in Taiwan (Keelung community-based integrated screening no. 12)
Population-based survey on prevalence of adult patients with epilepsy in Taiwan (Keelung community-based integrated screening no. 12)
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DOI：
10.1016/j.eplepsyres.2006.07.007
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发表时间：
2006-11-01
影响因子：
2.2
通讯作者：
Liou, Horng-Huei
中科院分区：
文献类型：
--
作者：
Chen, Chih-Chuan;Chen, Ta-Fu;Liou, Horng-Huei
目的：为了确定台湾成人癫痫患者的患病率和模式，我们进行了一项以社区为基础的神经流行病学调查。它被纳入社区健康筛查服务，并于2001年1月1日至2001年12月31日在台湾北方城市基隆进行。共有13,663名年龄在30岁以上的受试者参加了这项调查。其中活动性癫痫37例。30岁以上活动性癫痫的年龄校正患病率为2.77/1000（1980年美国人群），40-49岁受试者的患病率最高（4.0/1000）。男性患病率高于女性。最常见的发作类型为复杂部分性发作（46.0%）。采用一期检测法，我们发现9例（24.3%）活动性癫痫患者以前从未被诊断过。在活动性癫痫患者中，35.1%为症状性癫痫。脑损伤（13.5%）是主要原因，其次是中枢神经系统感染（8.1%），脑卒中（5.4%）和围产期损伤（5.4%）。30岁以上的癫痫终生患病率（包括癫痫活动期和癫痫缓解期）为3.14/1000。结论：与1993年的癫痫调查相比，我们的结果显示台湾北方地区癫痫的患病率在过去十年中相当稳定。头部损伤是导致活动性癫痫的主要原因。改善公共安全是一个重要的公共卫生问题，这可能有助于减少癫痫的发生。(c)2006 Elsevier B. V.保留所有权利。
Purpose: To determine the prevalence rate and patterns of adult patients with epilepsy in Taiwan, we conducted a community-based neuroepidemiological survey.Methods: Epilepsy was detected by neurologists using one-stage method. It was integrated into a community health screening service and performed from 1 January 2001 to 31 December 2001 in Keelung, a northern city in Taiwan. A total of 13,663 subjects aged 30 years or older participated in this survey.Results: There were 52 patients with epilepsy in this study. Among them, 37 were patients with active epilepsy. The age-adjusted prevalence rate of active epilepsy above 30 years old was 2.77/1000 (to the 1980 US population) with the highest rate in subjects aged 40-49 years (4.0/1000). There was a trend of higher prevalence rate in male than in female. The most common seizure type was complex partial seizure (46.0%). Using one-stage detection method, we found nine (24.3%) patients with active epilepsy who had never been diagnosed before. Among the patients with active epilepsy, 35.1% were symptomatic cases. Head injury (13.5%) is the leading cause, followed by CNS infection (8.1%), stroke (5.4%) and perinatal insult (5.4%). The lifetime prevalence rate of epilepsy (including active epilepsy and epilepsy in remission) was 3.14/1000 for age above 30 years.Conclusions: Comparing to previous epilepsy survey in 1993, our results showed that the prevalence rate of epilepsy was rather stable over the past decade in northern Taiwan. Head injury is the leading cause responsible for active epilepsy. Improving public safety is an important public health issue which may help to reduce occurrence of epilepsy. (c) 2006 Elsevier B.V. All rights reserved.