Postnatal development of onset transient responses in macaque V1 AND V2 neurons.
Postnatal development of onset transient responses in macaque V1 AND V2 neurons.
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DOI：
10.1152/jn.90446.2008
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发表时间：
2008-09
影响因子：
2.5
通讯作者：
Bin Zhang;Earl L. Smith;Y. Chino
中科院分区：
文献类型：
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作者：
Bin Zhang;Earl L. Smith;Y. Chino
新生儿的视觉是有限的，在他们的视觉大脑的不成熟。在成年灵长类动物中，视觉皮层神经元的瞬时放电被认为与视觉场景中快速连续的简短图像的捕获密切相关。在这里，我们试图确定初级视觉皮层（V1）和视觉区2（V2）的幼猴的单个神经元的瞬态反应的响应性和质量。我们发现，神经元放电到640毫秒的静止光栅的瞬态分量是强大的和可靠的成人出生后仅2周，而持续的组件是更缓慢的婴儿比成人。因此，支持发作瞬态反应的皮层回路在出生时功能成熟，我们的研究结果预测，新生儿，他们的“贫困的视力”，能够启动相对成熟的注视眼球运动和执行检测简单的对象远远好于传统的想法。
Vision of newborn infants is limited by immaturities in their visual brain. In adult primates, the transient onset discharges of visual cortical neurons are thought to be intimately involved with capturing the rapid succession of brief images in visual scenes. Here we sought to determine the responsiveness and quality of transient responses in individual neurons of the primary visual cortex (V1) and visual area 2 (V2) of infant monkeys. We show that the transient component of neuronal firing to 640-ms stationary gratings was as robust and as reliable as in adults only 2 wk after birth, whereas the sustained component was more sluggish in infants than in adults. Thus the cortical circuitry supporting onset transient responses is functionally mature near birth, and our findings predict that neonates, known for their "impoverished vision," are capable of initiating relatively mature fixating eye movements and of performing in detection of simple objects far better than traditionally thought.