Effect of Tympanic Perforations on the Detection of Distortion-product Otoacoustic Emissions

Effect of Tympanic Perforations on the Detection of Distortion-product Otoacoustic Emissions
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鼓膜穿孔对失真产物耳声发射检测的影响

DOI:
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发表时间:
2000
期刊:
Ear, nose, & throat journal
影响因子:
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通讯作者:
O. Malphurs
O. Malphurs
中科院分区:
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文献类型:
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作者:
H. W. Lebourgeois;Vinod K. Anand;J. Mcauley;J. Dickman;O. Malphurs

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畸变产物耳声发射(DPOAEs)的检测依赖于耳朵的传导装置的可行性。然而,鼓膜穿孔和其他传导性疾病还没有得到充分的调查方面的检查DPOAE。使用豚鼠模型,我们在鼓膜上制作不同大小和位置的穿孔,并收集每种条件下频率在2,193和5,508 Hz之间的DPOAE数据。我们发现,小穿孔,高达鼓膜面积的25%,仍然允许我们检测特定频率的发射。然而,50%及以上的穿孔,以及伴有创伤性外淋巴瘘和听骨关节脱位的穿孔,严重干扰了DPOAE的检测。我们讨论了DPOAEs的潜在用途,这些结果的临床相关性。
The detection of distortion-product otoacoustic emissions (DPOAEs) depends on the viability of the ear's conduction apparatus. However, tympanic membrane perforations and other conductive disorders have not been fully investigated with regard to the examination of DPOAEs. Using the guinea pig model, we made perforations of different sizes and loci on the tympanic membrane and collected DPOAE data for frequencies between 2,193 and 5,508 Hz for each condition. We found that small perforations, up to 25% of the area of the tympanic membrane, still allow us to detect emissions at the specified frequencies. However, perforations of 50% and larger, as well as those accompanied by traumatic perilymph fistulas and ossicular disarticulations, severely interfered with the detection of DPOAEs. We discuss the clinical relevance of these findings with respect to the potential uses of DPOAEs.
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