Diagnostic quality assessment of compressed sensing accelerated magnetic resonance neuroimaging
Diagnostic quality assessment of compressed sensing accelerated magnetic resonance neuroimaging
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DOI：
10.1002/jmri.25149
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发表时间：
2016-08-01
影响因子：
4.4
通讯作者：
Peters, Terry
中科院分区：
文献类型：
--
作者：
Kayvanrad, Mohammad;Lin, Amy;Peters, Terry
目的确定压缩感知（CS）重建在特定临床磁共振神经成像应用中的效果，超越更传统的加速技术，如平行成像（PI）和低分辨率采集。材料与方法5名健康志愿者的原始k空间数据采用32通道头线圈3T扫描仪，采用T-2-FLAIR、fista -c、飞行时间（TOF）和破坏梯度回波（SPGR）序列采集。在一系列盲法研究中，三位放射科医生独立评估了CS、PI （GRAPPA）和高达5倍加速度下的低分辨率图像。人工病变的合成T-2-FLAIR图像用于评估CS重建的诊断准确性。结果T-2-FLAIR和fista - c在高达4倍加速度时的重建质量诊断可接受（4倍加速度时的5分制平均定性评分分别为3.7和4.3分），TOF和SPGR在高达3倍加速度时的重建质量诊断可接受（3倍加速度时的平均评分分别为4.0和3.7分）。CS重建的定性评分显著优于T-2-FLAIR、fista - c和TOF的低分辨率图像，TOF和SPGR的定性评分显著优于GRAPPA (Wilcoxon符号秩检验，P < 0.05)，其他差异无统计学意义。CS和低分辨率图像在高达3倍加速度下的诊断准确性均可接受（ROC曲线下面积分别为0.97和0.96）。结论CS和PI联合重建可获得轻度至中度加速度。然而，对于某些序列/应用，可以通过适当降低成像分辨率来减少采集时间，而不是更复杂的CS重建。j .增效。的原因。成像2016;44:433 - 444。
PurposeTo determine the efficacy of compressed sensing (CS) reconstructions for specific clinical magnetic resonance neuroimaging applications beyond more conventional acceleration techniques such as parallel imaging (PI) and low-resolution acquisitions.Materials and MethodsRaw k-space data were acquired from five healthy volunteers on a 3T scanner using a 32-channel head coil using T-2-FLAIR, FIESTA-C, time of flight (TOF), and spoiled gradient echo (SPGR) sequences. In a series of blinded studies, three radiologists independently evaluated CS, PI (GRAPPA), and low-resolution images at up to 5x accelerations. Synthetic T-2-FLAIR images with artificial lesions were used to assess diagnostic accuracy for CS reconstructions.ResultsCS reconstructions were of diagnostically acceptable quality at up to 4x acceleration for T-2-FLAIR and FIESTA-C (average qualitative scores 3.7 and 4.3, respectively, on a 5-point scale at 4x acceleration), and at up to 3x acceleration for TOF and SPGR (average scores 4.0 and 3.7, respectively, at 3x acceleration). The qualitative scores for CS reconstructions were significantly better than low-resolution images for T-2-FLAIR, FIESTA-C, and TOF and significantly better than GRAPPA for TOF and SPGR (Wilcoxon signed rank test, P < 0.05) with no significant difference found otherwise. Diagnostic accuracy was acceptable for both CS and low-resolution images at up to 3x acceleration (area under the ROC curve 0.97 and 0.96, respectively.)ConclusionMild to moderate accelerations are possible for those sequences by a combined CS and PI reconstruction. Nevertheless, for certain sequences/applications one might mildly reduce the acquisition time by appropriately reducing the imaging resolution rather than the more complicated CS reconstruction. J. Magn. Reson. Imaging 2016;44:433-444.