Research progress of pharmacological effects of Siraitia grosvenorii extract

Research progress of pharmacological effects of Siraitia grosvenorii extract
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DOI:
10.1093/jpp/rgab150
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发表时间:
2021
期刊:
Journal of Pharmacy and Pharmacology
影响因子:
--
通讯作者:
Liming Zhou
Liming Zhou
中科院分区:
--
文献类型:
--
作者:
He Li;Ruli Li;Wei Jiang;Liming Zhou

文献摘要

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Abstract. Objectives. To summarise the ingredients of Luo Han Guo extract and the different pharmacological activity of the different ingredients. Find and evaluate the research value of Luo Han Guo extract as a therapeutic drug.. Key findings. Siraitia grosvenorii is a fruit native to China and has many years of medicinal history. Because of its low-calorie and sugar-free properties, it is approved as a sweetener substitute in foods for obese and diabetic patients. Experiments have shown that this sweetener is non-toxic. This article summarises much literature on S. grosvenorii extracts, briefly introduces their chemical composition and metabolic distribution and summarises the possible pharmacological effects of each S. grosvenorii extract. Siraitia grosvenorii extract has anti-diabetic, anti-tumour, anti-inflammatory, antioxidant, neuroprotective and lipogenic inhibitory effects. These pharmacological activities suggest the medicinal value of S. grosvenorii.. Summary. Luo Han Guo extract is a low-calorie, non-toxic substance, and its pharmacological activity and its potential medicinal properties support its further utilisation and research.