Dynamic inversion time for improved 3D late gadolinium enhancement imaging in patients with atrial fibrillation.
Dynamic inversion time for improved 3D late gadolinium enhancement imaging in patients with atrial fibrillation.
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DOI：
10.1002/mrm.25190
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发表时间：
2015-02
影响因子：
3.3
通讯作者：
Firmin DN
中科院分区：
文献类型：
--
作者：
Keegan J;Gatehouse PD;Haldar S;Wage R;Babu-Narayan SV;Firmin DN
采用单R波门控进行高分辨率3D晚期钆增强（LGE）成像，以最大限度地减少冗长的采集持续时间。在房颤（AF）患者中，心率变异性导致序列重复之间的可变磁化恢复，并且图像质量通常较差。在这项研究中，我们实施和测试了一个动态反转时间方案，旨在降低序列的敏感性，心率变化。对反转准备的3D分段梯度回波序列进行了修改，以便反转时间（TI）根据自上次序列重复以来的时间自动从心跳到心跳（动态TI）变化。17例患者在持续性房颤射频消融前进行了3D LGE采集，包括有和无动态TI。比较定性图像质量评分、血信号与重影比（SGR）和血心肌对比度与重影比（CGR）。动态TI的图像质量评分高于无动态TI的图像质量评分（2.2 +/-0.9 vs 1.8 +/-1.1，p = 0.008），血心肌CGR（13.8 +/-7.6 vs 8.3 +/-6.1，p = 0.003）和血SGR（19.6 +/-8.5 vs 13.1 +/-8.0，p = 0.003）也是如此。动态TI算法通过降低序列对RR间期变化的敏感性，改善了该困难患者人群中3D LGE成像的图像质量。
High resolution 3D late gadolinium enhancement (LGE) imaging is performed with single R-wave gating to minimise lengthy acquisition durations. In patients with atrial fibrillation (AF), heart rate variability results in variable magnetisation recovery between sequence repeats and image quality is often poor. In this study, we implemented and tested a dynamic inversion time scheme designed to reduce sequence sensitivity to heart rate variations. An inversion-prepared 3D segmented gradient echo sequence was modified so that the inversion time (TI) varied automatically from beat-to-beat (dynamic-TI) based on the time since the last sequence repeat. 3D LGE acquisitions were performed in 17 patients prior to RF ablation of persistent AF both with and without dynamic-TI. Qualitative image quality scores, blood signal-to-ghosting ratios (SGRs) and blood-myocardium contrast-to-ghosting ratios (CGRs) were compared. Image quality scores were higher with dynamic-TI than without (2.2 +/− 0.9 versus 1.8 +/− 1.1, p = 0.008) as were blood-myocardium CGRs (13.8 +/− 7.6 versus 8.3 +/− 6.1, p = 0.003) and blood SGRs (19.6 +/− 8.5 versus 13.1 +/− 8.0, p = 0.003). The dynamic-TI algorithm improves image quality of 3D LGE imaging in this difficult patient population by reducing the sequence sensitivity to RR interval variations.