Traumatic dysesthesia of the trigeminal nerve.
Traumatic dysesthesia of the trigeminal nerve.
复制标题
三叉神经外伤性感觉迟钝。
作者：
D. Canavan;S. Graff‐Radford;B. Gratt
周围神经的创伤性损伤通常会导致持续的不适。 P 物质被认为是疼痛的介质，并且这种神经递质的消耗已被证明可以减轻疼痛。患有三叉神经外伤性感觉异常的受试者接受辣椒素治疗，辣椒素是一种具有显着长期效果的 P 物质消耗剂。这种形式的治疗可以单独使用或与其他药物干预联合使用来治疗创伤性三叉神经感觉异常。
Traumatic injury to the peripheral nerves often results in persistent discomfort. Substance P has been implicated as a mediator of pain, and depletion of this neurotransmitter has been shown to reduce pain. Subjects suffering from traumatic dysesthesia of the trigeminal nerve were treated with capsaicin, a substance P depleter with significant long-term effects. This form of therapy may be used individually or in combination with other pharmacologic interventions in the treatment of traumatic trigeminal dysesthesia.