Determinants of Frailty

Determinants of Frailty
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DOI:
10.1016/j.jamda.2009.11.008
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发表时间:
2010-06-01
影响因子:
7.6
通讯作者:
Schols, Jos M. G. A.
Schols, Jos M. G. A.
中科院分区:
医学1区
文献类型:
--
作者:
Gobbens, Robbert J. J.;van Assen, Marcel A. L. M.;Schols, Jos M. G. A.

文献摘要

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目的:为了确定哪些决定因素预测脆弱和脆弱的领域(生理,心理,社会)在一个社区居住的老年人样本。设计:横截面。设置:社区为基础。参与者:一个有代表性的样本484社区居住的人年龄在75岁以上。测量:蒂尔堡虚弱指标(TFI)是一种自我报告问卷,用于收集有关虚弱决定因素的信息,并评估虚弱和虚弱领域(身体、心理、社会)。结果:通过回归和中介分析获得结果。这10个决定因素解释了脆弱性变异的35%。在控制了其他决定因素后,中等收入、不健康的生活方式和多次死亡预示着脆弱。其他决定因素的影响不同域的脆弱;年龄预测身体脆弱,生活事件预测心理脆弱,而作为一个女人预测社会脆弱,因为老年妇女有较高的概率livingalone.Conclusion:我们的发现,脆弱的决定因素的影响不同的脆弱域表明,它是必不可少的划分到域的概念脆弱。(《美国医学发展杂志》,2010年; 11:356-364)
Objectives: To determine which determinants predict frailty and domains of frailty (physical, psychological, social) in a community-dwelling sample of elderly persons.Design: Cross-sectional.Setting: Community-based.Participants: A representative sample of 484 community-dwelling persons aged 75 years and older.Measurements: The Tilburg Frailty Indicator (TFI), a self-report questionnaire, was used to collect information about determinants of frailty and to assess frailty and domains of frailty (physical, psychological, social).Results: Results were obtained by regression and mediation analyses. The 10 determinants explain about 35% of the variance of frailty. After controlling for other determinants, medium income, an unhealthy lifestyle, and multimorbidity predicted frailty. The effects of other determinants differed across domains of frailty; age predicted physical frailty, life events predicted psychological frailty, whereas being a woman predicted social frailty because older women have a higher probability of living alone.Conclusion: Our finding that the effect of the determinants of frailty differs across frailty domains suggests that it is essential to divide the concept of frailty into domains. (J Am Med Dir Assoc 2010; 11: 356-364)