LOCALIZATION OF A CIRCADIAN PACEMAKER IN THE EYE OF A MOLLUSK, BULLA
LOCALIZATION OF A CIRCADIAN PACEMAKER IN THE EYE OF A MOLLUSK, BULLA
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DOI：
10.1126/science.217.4555.155
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发表时间：
1982-01-01
期刊：
影响因子：
56.9
通讯作者：
WALLACE, SF
中科院分区：
文献类型：
--
作者：
BLOCK, GD;WALLACE, SF
海洋软体动物大泡的眼睛含有一个昼夜节律起搏器，它与关键的夹带路径一起位于视网膜底部的一小群神经元中。构成视网膜体积大部分的有组织的感光层细胞的长期细胞内记录表明，这些细胞不参与节律的产生，因为没有观察到膜电位的节律变化。手术切除整个感光层不会改变昼夜节律的周期，也不会阻止光脉冲引起的相移。
The eye of the marine mollusk Bulla contains a circadian pacemaker which, along with critical entrainment pathways, is located among a small group of neurons at the base of the retina. Long-term intracellular recording from cells of the organized photoreceptor layer, which constitutes most of the retinal volume, indicates that these cells are not involved in generating the rhythm since rhythmic changes in membrane potential were not observed. Surgical removal of the entire photoreceptor layer does not alter the period of the circadian rhythm and does not prevent phase shifts by light pulses.