Synovitis of recent onset. A clinicopathologic study during the first month of disease.
Synovitis of recent onset. A clinicopathologic study during the first month of disease.
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最近发病的滑膜炎。
DOI：
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发表时间：
1972
影响因子：
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通讯作者：
Rodanthi C. Kitridou
中科院分区：
文献类型：
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作者：
H. Schumacher;Rodanthi C. Kitridou
在滑膜炎第一个月进行研究的 24 名患者中，有 9 名随后满足成人或青少年类风湿性关节炎的诊断标准。大多数表现出明显的滑膜血管病变和炎症，很少包括浆细胞。类风湿因子滴度低，但丙种球蛋白水平常常升高。滑液白细胞计数通常低于慢性 RA，即使有非炎性积液，也可见滑膜炎症。九名患者患有暂时性滑膜炎，不符合任何已知的疾病实体。
Nine of 24 patients studied during the first month of synovitis subsequently fulfilled diagnostic criteria for adult or juvenile rheumatoid arthritis. Most showed prominent synovial vascular lesions and inflammation that rarely included plasma cells. Rheumatoid factor titers were low, but gammaglobulin levels were often elevated. Synovial fluid leukocyte counts were generally lower than in chronic RA, and synovial membrane inflammation was seen even with noninflammatory effusions. Nine patients had a transient synovitis not fitting any known disease entity.