Development of acid-catalyzed fluorous benzylating reagents based on a triazinedione core
Development of acid-catalyzed fluorous benzylating reagents based on a triazinedione core
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DOI：
10.1016/j.jfluchem.2016.09.003
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发表时间：
2016-10
影响因子：
1.9
通讯作者：
M. Kunishima;Ryohei Asao;Kohei Yamada;M. Kitamura;Hikaru Fujita
中科院分区：
文献类型：
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作者：
M. Kunishima;Ryohei Asao;Kohei Yamada;M. Kitamura;Hikaru Fujita
基于三嗪二酮独特的缺π电子特性，开发了酸催化氟代苄基化试剂。通过在催化量的三氟甲磺酸存在下使用这些试剂，醇和羧酸可以分别以良好的产率转化成相应的氟苄基醚和酯衍生物。
Acid-catalyzed fluorous benzylating reagents have been developed based on the unique π-electron deficient properties of triazinedione. Alcohols and carboxylic acids could be converted into the corresponding fluorous-benzyl ether and ester derivatives, respectively, in good yield by using the reagents in the presence of a catalytic amount of trifluoromethanesulfonic acid.