Design and Implementation of a Laboratory-Based Drug Design and Synthesis Advanced Pharmacy Practice Experience
Design and Implementation of a Laboratory-Based Drug Design and Synthesis Advanced Pharmacy Practice Experience
复制标题
DOI：
10.5688/ajpe79343
复制
发表时间：
2015-04
影响因子：
3.3
通讯作者：
Ashok Philip;Mark Stephens;Sheila L. Mitchell
中科院分区：
文献类型：
--
作者：
Ashok Philip;Mark Stephens;Sheila L. Mitchell
客观的。为学生提供在药学博士（PharmD）课程内参与药物化学研究的机会。设计。我们为药学学生设计并实施了药物设计或药物合成的 3 门课程，包括 1 个月的高级选修课和两门为期 1 个月的研究高级药学实践体验 (APPE)。为了最大限度地提高学生的参与度，这个包含 3 门课程的课程每年向三年级和四年级学生提供两次。评估。根据学生对项目成功、生产力和专业精神的承诺进行评估。学生还使用包含 14 项的课程评估标准来评估课程顺序。学生的反馈非常积极。学生们发现这种经历是他们药学课程的宝贵组成部分。结论。我们成功设计并实施了一个 3 门课程的研究序列，让传统 4 年制课程的药学博士学生能够参与药物设计和合成研究。学生们表示，该序列增强了他们的批判性思维和解决问题的能力，并帮助他们发展为独立学习者。基于该序列所取得的成功，正在努力开发制药科学其他领域的研究 APPE。
Objective. To provide students with an opportunity to participate in medicinal chemistry research within the doctor of pharmacy (PharmD) curriculum. Design. We designed and implemented a 3-course sequence in drug design or drug synthesis for pharmacy students consisting of a 1-month advanced elective followed by two 1-month research advanced pharmacy practice experiences (APPEs). To maximize student involvement, this 3-course sequence was offered to third-year and fourth-year students twice per calendar year. Assessment. Students were evaluated based on their commitment to the project’s success, productivity, and professionalism. Students also evaluated the course sequence using a 14-item course evaluation rubric. Student feedback was overwhelmingly positive. Students found the experience to be a valuable component of their pharmacy curriculum. Conclusion. We successfully designed and implemented a 3-course research sequence that allows PharmD students in the traditional 4-year program to participate in drug design and synthesis research. Students report the sequence enhanced their critical-thinking and problem-solving skills and helped them develop as independent learners. Based on the success achieved with this sequence, efforts are underway to develop research APPEs in other areas of the pharmaceutical sciences.