Planimetry of mitral valve stenosis by magnetic resonance imaging

Planimetry of mitral valve stenosis by magnetic resonance imaging
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DOI:
10.1016/j.jacc.2005.03.036
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发表时间:
2005-06-21
影响因子:
24
通讯作者:
Luchner, A
Luchner, A
中科院分区:
医学1区
文献类型:
--
作者:
Djavidani, B;Debl, K;Luchner, A

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我们试图确定通过磁共振成像(MRI)对二尖瓣狭窄(MS)患者进行二尖瓣面积(MVA)的无创平面测量是否可行和可靠。背景MVA的准确评估对于瓣膜狭窄患者的管理尤为重要。目前的标准技术,用于评估MS的严重程度,包括超声心动图(ECHO)和心导管(CATH)。方法在22例疑似或已知MS,MVA面积测量进行了1.5 T磁共振扫描仪使用屏气平衡梯度回波序列(真FISP)。结果MRI和CATH-MVA之间的相关性为0.89(p < 0.0001),MRI和ECHO-MVA之间的相关性为0.81(p <0.0001)。MRI-MVA略微高估CATH-MVA 5.0%(1.60 +/- 0.45 cm(2)vs. 1.52 +/- 0.49 cm(2),p = NS),ECHO-MVA高估8.1%(1.61 +/- 0.42 cm(2)vs. 1.48 +/- 0.42 cm(2),P < 0.05)。在受试者工作特征曲线分析中,MRI-MVA值低于1.65cm2提示二尖瓣狭窄(CATH-MVA
OBJECTIVES We sought to determine whether noninvasive planimetry of the mitral valve area (MVA) by magnetic resonance imaging (MRI) is feasible and reliable in patients with mitral stenosis (MS).BACKGROUND Accurate assessment of MVA is particularly important for the management of patients with valvular stenosis. Current standard techniques for assessing the severity of MS include echocardiography (ECHO) and cardiac catheterization (CATH).METHODS In 22 patients with suspected or known MS, planimetry of MVA was performed with a 1.5-T magnetic resonance scanner using a breath-hold balanced gradient echo sequence (true FISP). Data were compared with echocardiographically determined MVA (ECHO-MVA, n = 22), as well as with invasively calculated MVA by the Gorlin-formula at (CATH-MVA, n = 17).RESULTS The correlation between MRI- and CATH-MVA was 0.89 (p < 0.0001), and the correlation between MRI- and ECHO-MVA was 0.81 (p < 0.0001). The MRI-MVA slightly overestimated CATH-MVA by 5.0% (1.60 +/- 0.45 cm(2) VS. 1.52 +/- 0.49 cm(2), p = NS) and ECHO-MVA by 8.1% (1.61 +/- 0.42 cm(2) VS. 1.48 +/- 0.42 cm(2), P < 0.05). On receiver-operating characteristic curve analysis, a value of MRI-MVA below 1.65 cm 2 indicated mitral stenosis (CATH-MVA