Long-term efficacy of pulmonary rehabilitation with home-based or low frequent maintenance programs in patients with chronic obstructive pulmonary disease: a meta-analysis
Long-term efficacy of pulmonary rehabilitation with home-based or low frequent maintenance programs in patients with chronic obstructive pulmonary disease: a meta-analysis
复制标题
DOI：
10.21037/apm-19-581
复制
发表时间：
2020-09-01
影响因子：
--
通讯作者：
Tatsumi, Koichiro
中科院分区：
文献类型：
--
作者：
Imamura, Soh;Inagaki, Takeshi;Tatsumi, Koichiro
背景：慢性阻塞性肺疾病(COPD)患者肺康复(PR)的短期疗效已经确定。虽然持续的随访和持续的运动训练对维持疗效很重要，但在没有频繁监督训练的情况下，PR的长期疗效仍不清楚。这项荟萃分析的目的是探讨PR加家庭或低频率维护计划对慢性阻塞性肺疾病患者运动能力和健康相关生活质量(HRQOL)的长期疗效。方法：我们确定了随机对照试验(RCT)，比较了PR与家庭或低频率维护以及来自PubMed和Cochrane图书馆的无维护计划的长期疗效。主要结果是运动能力[6分钟步行距离(6MWD)、递增穿梭步行试验(ISWT)]和HRQOL[圣乔治呼吸问卷(SGRQ)]。结果使用随机效应模型进行组合。结果：7个随机对照试验，共492例COPD患者符合纳入标准。6MWD[平均差值(MD)27.00；95%CI：1.0452.96；P=0.01]和ISWT(MD44.48；95%CI：30.7058.25；P
Background: The short-term efficacy of pulmonary rehabilitation (PR) in patients with chronic obstructive pulmonary disease (COPD) has been established. Although continuous follow-up and sustained exercise training is important to maintain the effects, the long-term efficacy of PR without frequent supervised training remains unclear. The aim of this meta-analysis was to investigate the long-term efficacy of PR with home-based or low frequent maintenance program on exercise capacity and health related quality of life (HRQOL) in patients with COPD.Methods: We identified randomized controlled trials (RCTs) comparing long-term efficacy of PR with home-based or low frequent maintenance and no maintenance program from PubMed and the Cochrane Library. Primary outcomes were exercise capacity [6-minute walking distance (6MWD), incremental shuttle walking test (ISWT)] and HRQOL [St. Georges Respiratory Questionnaire (SGRQ)]. Outcomes were combined using a random-effects model. This study is registered with PROSPERO, number CRD42019109718.Results: Seven RCTs with a total of 492 patients with COPD met the inclusion criteria. PR with maintenance significantly improved 6MWD [mean difference (MD) 27.00; 95% CI: 1.0452.96; P=0.01] and ISWT (MD 44.48; 95% CI: 30.7058.25; P