Anterior prefrontal cortex and the recollection of contextual information
Anterior prefrontal cortex and the recollection of contextual information
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DOI：
10.1016/j.neuropsychologia.2005.02.004
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发表时间：
2005-01-01
期刊：
影响因子：
2.6
通讯作者：
Burgess, PW
中科院分区：
文献类型：
--
作者：
Simons, JS;Owen, AM;Burgess, PW
回忆性记忆可以涉及检索许多不同类型的上下文信息，包括事件发生的地点和时间，以及我们当时的想法和感受。在一项与事件相关的功能性磁共振成像实验中，研究人员对与这种能力相关的大脑区域进行了检查。在这项实验中，参与者对显示在监视器屏幕左侧或右侧的单词或著名面孔做出了决定。随后，研究人员再次展示了研究过的单词和面孔，参与者接受了fMRI大脑扫描，同时回忆他们对每个项目做出的决定（“任务记忆”），或者是在屏幕的左边还是右边（“位置记忆”）。在前额叶皮层（主要是布罗德曼10区）内观察到功能分离，与记忆任何类型的信息（相对于基线）相关的外侧区域激活，并且在“任务记忆”条件下，内侧前PFC区域显示出显著更大的激活。这些结果表明，不同的角色，外侧和内侧前额叶皮层在回忆。(c)2005爱思唯尔有限公司保留所有权利。
Recollective memory can involve the retrieval of many different kinds of contextual information, including where and when an event took place, as well as our thoughts and feelings at the time. The brain regions associated with this ability were examined in an event-related fMRI experiment, where participants made decisions about words or famous faces which were presented either on the left or right of a monitor screen. Subsequently, the studied words and faces were again presented and participants underwent fMRI brain scanning while recollecting either which of the decisions they had made on each item ("task memory"), or whether it had been presented on the left or right of the screen ("position memory"). A functional dissociation was observed within anterior prefrontal cortex (principally Brodmann's area 10), with activation in lateral regions associated with remembering either type of information (relative to baseline), and a medial anterior PFC region showing significantly greater activation during the "task memory" conditions. These results suggest different roles for lateral and medial anterior prefrontal cortex in recollection. (c) 2005 Elsevier Ltd. All rights reserved.