Effects on growth performance, faecal microflora and plasma cholesterol after supplementation of spray-dried metabolite to postweaning rats
Effects on growth performance, faecal microflora and plasma cholesterol after supplementation of spray-dried metabolite to postweaning rats
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DOI：
10.17221/1738-cjas
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发表时间：
2009-01-01
影响因子：
1.2
通讯作者：
Law, F. L.
中科院分区：
文献类型：
--
作者：
Loh, T. C.;Chong, S. W.;Law, F. L.
进行了一项研究，以研究饲喂由Lb产生的喷雾干燥的代谢物（SDM）的影响。植物乳杆菌I-UL 4对断奶后大鼠的生长性能、粪便pH、粪便中肠杆菌科细菌和乳酸菌（LAB）计数以及血浆胆固醇浓度的影响。将15只4周龄雌性Sprague道利大鼠随机分为3组：基础饲料（对照）、0.25%SDM和0.5%SDM饲料。测定日采食量、日生长率、血浆总胆固醇浓度、粪便肠杆菌和乳酸菌。各处理组间的生长率、总采食量、饲料转化率和pH值差异不显著（P > 0.05）。0.25%和0.5%组粪便中肠杆菌科细菌计数显著低于对照组（P < 0.05）。但各处理组间乳酸菌计数无显著性差异（P > 0.05）。血浆胆固醇浓度显著降低（P < 0.05）。对照组的胆固醇浓度最高。然而，0.5%SDM组的血浆胆固醇浓度最低，其次是0.25%SDM组。
A study was conducted to study the effects of feeding a spray-dried metabolite (SDM) produced by Lb. plantarum I-UL4 in the diets of postweaning rats on growth performance, faecal pH, Enterobacteriaceae bacterial and lactic acid bacteria (LAB) counts in the faeces and on plasma cholesterol concentrations. A total of 15 female 4-weeks-old Sprague dawley rats were randomly assigned to 3 groups of diets: basal diet (control), 0.25% SDM and 0.5% SDM diets. Daily feed intake, daily growth rate, blood plasma for total cholesterol concentration and faecal Enterobacteriaceae and LAB were measured. The growth rate, total feed intake, feed conversion ratio, and pH were not significantly different (P > 0.05) among all the treatment groups. The faecal Enterobacteriaceae counts in the 0.25% and 0.5% groups were significantly (P < 0.05) lower than in the control group. However, there was no significant difference (P > 0.05) in the LAB counts among all the treatment groups. The plasma cholesterol concentration was significantly reduced (P < 0.05) following the feeding of the metabolite. The control had the highest concentration of cholesterol. However, the 0.5% SDM group had the lowest plasma cholesterol concentration, followed by the 0.25% SDM group.