Screening men for Chlamydia trachomatis infection: have we fully explored the possibilities?
Screening men for Chlamydia trachomatis infection: have we fully explored the possibilities?
复制标题
筛查男性沙眼衣原体感染：我们是否充分探索了可能性？
DOI：
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发表时间：
2000
期刊：
影响因子：
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通讯作者：
K. Fenton
中科院分区：
文献类型：
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作者：
K. Fenton
生殖器衣原体感染是英格兰和威尔士最常见的可治愈的性传播疾病。它是盆腔炎、宫外孕和不孕症的主要原因。因此，研究、健康促进和疾病预防举措都以妇女为重点。对妇女进行衣原体感染筛查主要是为了查明和减少已感染者的并发症（二级预防），而不是为了防止新的感染（一级预防）。筛查男性生殖器衣原体感染是预防女性新感染的一项策略，但由于成本高、采样程序侵入性大以及需要在临床环境中进行筛查，因此被认为存在问题。核酸扩增诊断测试的可用性挑战了这些局限性，并为积极将男性纳入疾病预防提供了新的机会。本文回顾了支持和反对筛查男性生殖器衣原体感染的论点，并讨论了实施的可能策略。
Genital chlamydial infection is the commonest curable sexually transmitted disease in England and Wales. It is a major cause of pelvic inflammatory disease, ectopic pregnancy, and infertility. For this reason, research, health promotion, and disease prevention initiatives have focused on women. Screening women for chlamydial infection is concerned mainly with identifying and reducing complications among those already infected (secondary prevention), rather than with preventing new infections (primary prevention). Screening men for genital chlamydial infection, a strategy for preventing new infections in women, has been considered problematic because of the cost, the invasiveness of sampling procedures, and the need to screen in clinical settings. The availability of nucleic acid amplification diagnostic tests challenges these limitations and offers new opportunities for actively including men in disease prevention. This article reviews the arguments for and against screening men for genital chlamydial infection and discusses possible strategies for its implementation.