Neural correlates of admiration and compassion
Neural correlates of admiration and compassion
复制标题
DOI：
10.1073/pnas.0810363106
复制
发表时间：
2009-05-12
影响因子：
11.1
通讯作者：
Damasio, Antonio
中科院分区：
文献类型：
--
作者：
Immordino-Yang, Mary Helen;McColl, Andrea;Damasio, Antonio
在一项功能磁共振成像实验中，参与者被暴露在基于真实故事的叙述中，这些故事旨在唤起4种不同类别的钦佩和同情：对美德的钦佩（AV），对技能的钦佩（AS），对社会/心理疼痛的同情（CSP）和对身体疼痛的同情（CPP）。目的是检验关于在疼痛相关（同情）和非疼痛相关（钦佩）的社会情绪沿着2个维度处理过程中招募稳态、躯体感觉和意识相关神经系统的假设：关于他人社会/心理状况的情绪（AV、CSP）和关于他人身体状况的情绪（AS、CPP）。与理论解释相一致，所有4种情绪的体验都涉及参与内感受表征和稳态调节的大脑区域，包括前扣带回、前扣带回、下丘脑和中脑。然而，这项研究也揭示了一个以前没有描述过的模式，（楔前叶，后扣带皮层和压后区的整体），这是一个有趣的区域，目前已知其参与大脑操作的默认模式和自我相关/意识过程：与社会/心理和身体状况有关的情绪分别涉及不同的网络，有内感受和外感受神经系统。最后，在前额叶内，与AV和CSP相关的活动峰值较晚，并且比与CPP相关的活动更持久。我们的研究结果有助于了解后内侧皮质的功能以及前脑岛在与身体和心理疼痛相关的社会情绪中的募集。
In an fMRI experiment, participants were exposed to narratives based on true stories designed to evoke admiration and compassion in 4 distinct categories: admiration for virtue (AV), admiration for skill (AS), compassion for social/psychological pain (CSP), and compassion for physical pain (CPP). The goal was to test hypotheses about recruitment of homeostatic, somatosensory, and consciousness-related neural systems during the processing of pain-related (compassion) and non-pain-related (admiration) social emotions along 2 dimensions: emotions about other peoples' social/psychological conditions (AV, CSP) and emotions about others' physical conditions (AS, CPP). Consistent with theoretical accounts, the experience of all 4 emotions engaged brain regions involved in interoceptive representation and homeostatic regulation, including anterior insula, anterior cingulate, hypothalamus, and mesencephalon. However, the study also revealed a previously undescribed pattern within the posteromedial cortices (the ensemble of precuneus, posterior cingulate cortex, and retrosplenial region), an intriguing territory currently known for its involvement in the default mode of brain operation and in self-related/consciousness processes: emotions pertaining to social/psychological and physical situations engaged different networks aligned, respectively, with interoceptive and exteroceptive neural systems. Finally, within the anterior insula, activity correlated with AV and CSP peaked later and was more sustained than that associated with CPP. Our findings contribute insights on the functions of the posteromedial cortices and on the recruitment of the anterior insula in social emotions concerned with physical versus psychological pain.