Synthesis and cytotoxicity of a salicylihalamide A analogue.
Synthesis and cytotoxicity of a salicylihalamide A analogue.
复制标题
水杨酰卤酰胺 A 类似物的合成和细胞毒性。
DOI:
10.1021/np070694q
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发表时间:
2008
影响因子:
5.1
通讯作者:
Erickson,KarenL
中科院分区:
文献类型:
--
作者:
Tang,Shaoshan;Erickson,KarenL
The synthesis of a simple analogue of salicylihalamide A with a truncated lactone ring (±2) was achieved in 10 steps. Its cytotoxicity profile in the NCI 60-cell-line human tumor assay differed significantly from that of salicylihalamide A in both level and specificity.