Human Papilloma Virus in Multifocal, Invasive Female Genital Tract Malignancy
Human Papilloma Virus in Multifocal, Invasive Female Genital Tract Malignancy
复制标题
人乳头瘤病毒在多灶性、侵袭性女性生殖道恶性肿瘤中的应用
DOI：
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发表时间：
1983
影响因子：
7.2
通讯作者：
S. J. Daniel
中科院分区：
文献类型：
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作者：
J. Weed;C. Lozier;S. J. Daniel
两个年轻的患者多灶性，浸润性，疣状癌的下生殖道的描述。通过透射电子显微镜检查，在挖空细胞恶性和非恶性上皮细胞中发现了与人乳头状瘤病毒一致的病毒颗粒，两例患者均有免疫功能受损的证据。人乳头瘤病毒在生殖器肿瘤中的作用进行了讨论。
Two young patients with multifocal, invasive, verrucoid carcinomas of the lower genital tract are described. Viral particles consistent with human papilloma virus were demonstrated by transmission electron microscopy in areas of koilocytotic malignant and nonmalignant epithelium, and both patients had evidence of impaired immune function. The role of human papilloma virus in genital neoplasia is discussed.