Protein methylation: a signal event in post-translational modification
Protein methylation: a signal event in post-translational modification
复制标题
DOI：
10.1016/s0968-0004(98)01185-2
复制
发表时间：
1998-03-01
影响因子：
13.8
通讯作者：
Ettinger, MJ
中科院分区：
文献类型：
--
作者：
Aleta, JM;Cimato, TR;Ettinger, MJ
图1蛋白质氨基酸成分甲基化的例子。(A)精氨酸可以是一甲基化或二甲基化，后者有对称和不对称构型。(B)赖氨酸-氮的甲基化以单甲基化、二甲基化或三甲基化的形式发生。(C)许多G蛋白和蛋白磷酸酶2A的催化亚单位(PP2Ac)在蛋白质的C端羧基上甲基化。RT是G蛋白中的异丙基半胱氨酸，或PP2Ac中的亮氨酸。
Figure 1 Examples of the methylation of amino acid constituents of proteins.(a) Arginine can be either monoor dimethylated, the latter in symmetric and asymmetric configurations.(b) Methylation of the-nitrogen of lysine is known to occur as mono-, di-or trimethylated forms.(c) Many G proteins and the catalytic subunit of protein phosphatase 2A (PP2Ac) are methylated on the C-terminal carboxyl group of the protein. Rt is isoprenylcysteine in the G proteins, or leucine in PP2Ac.