Preliminary fMRI evidence of visual system dysfunction in Parkinson's disease patients with visual hallucinations

Preliminary fMRI evidence of visual system dysfunction in Parkinson's disease patients with visual hallucinations
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DOI:
10.1176/appi.neuropsych.18.3.402
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发表时间:
2006-06-01
影响因子:
2.9
通讯作者:
Wooten, G. Frederick
Wooten, G. Frederick
中科院分区:
医学4区
文献类型:
--
作者:
Holroyd, Suzanne;Wooten, G. Frederick

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使用功能磁共振成像(FMRI),作者检查了帕金森病患者的视皮层功能,这些患者有和没有经历过视觉幻觉。有视觉幻觉的患者表现出视觉关联皮质的激活增加和初级视觉皮质的缺陷,这表明视觉幻觉与视觉皮质功能的异常有关。
Using functional magnetic resonance imaging (fMRI), the authors examined visual cortex function in Parkinson's disease patients who did and did not experience visual hallucinations. Patients with visual hallucinations demonstrated increased activation in the visual association cortex and deficits in the primary visual cortex, suggesting that visual hallucinations are associated with an abnormality of visual-cortex function.