STOP questionnaire - A tool to screen patients for obstructive sleep apnea
STOP questionnaire - A tool to screen patients for obstructive sleep apnea
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DOI：
10.1097/aln.0b013e31816d83e4
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发表时间：
2008-05-01
期刊：
影响因子：
8.8
通讯作者：
Shapiro, Colin M.
中科院分区：
文献类型：
--
作者：
Chung, Frances;Yegneswaran, Balaji;Shapiro, Colin M.
背景：阻塞性陡峭呼吸暂停(OSA)是围手术期不良事件的主要危险因素。然而，还没有OSA的筛查工具在外科患者中得到验证。本研究旨在编制和验证一份简明易用的OSA筛查问卷。方法：在医院伦理批准后，招募年龄在18岁及以上且无OSA的术前患者。经过因素分析、信度检验和先导性研究后，使用四个是/否问题来开发该筛查工具。这四个问题分别与打呼、白天疲倦、观察到的呼吸暂停和高血压(STOP)有关。结果：2467例患者接受了STOP问卷调查，27.5%的患者被归类为阻塞性睡眠呼吸暂停低通气综合征的高危人群。211名患者接受了多导睡眠监测，34名患者进行了初步测试，177名患者进行了验证。在验证组中，呼吸暂停低通气指数为20+/-6。以呼吸暂停低通气指数大于5、大于15和大于30为界值的停止问卷的敏感度分别为65.6%、74.3%和79.5%。当将体重指数、年龄、颈围和性别纳入STOP问卷时，敏感性分别提高到83.6%、92.9%和100%，在相同的呼吸暂停-低通气指数界值下。结论：STOP问卷是一种简洁、易用的OSA筛查工具。它已经在手术前诊所的外科患者中得到了开发和验证。结合体重指数、年龄、颈部大小、性别，具有较高的敏感性，尤其对中重度阻塞性睡眠呼吸暂停综合征患者。
Background: Obstructive steep apnea (OSA) is a major risk factor for perioperative adverse events. However, no screening tool for OSA has been validated in surgical patients. This study was conducted to develop and validate a concise and easy-to-use questionnaire for OSA screening in surgical patients.Methods: After hospital ethics approval, preoperative patients aged 18 yr or older and without previously diagnosed OSA were recruited. After a factor analysis, reliability check, and pilot study; four yes/no questions were used to develop this screening tool. The four questions were respectively related to snoring, tiredness during daytime, observed apnea, and high blood pressure (STOP). For validation, the score from the STOP questionnaire was evaluated versus the apnea-hypopnea index from monitored polysomnography.Results: The STOP questionnaire was given to 2,467 patients, 27.5% classified as being at high risk of OSA. Two hundred eleven patients underwent polysomnography, 34 for the pilot test and 177 for validation. In the validation group, the apnea-hypopnea index was 20 +/- 6. The sensitivities of the STOP questionnaire with apnea-hypopnea index greater than 5, greater than 15, and greater than 30 as cutoffs were 65.6, 74.3, and 79.5%, respectively. When incorporating body mass index, age, neck circumference, and gender into the STOP questionnaire, sensitivities were increased to 83.6, 92.9, and 100% with the same apnea-hypopnea index cutoffs.Conclusions: The STOP questionnaire is a concise and easy-to-use screening tool for OSA. It has been developed and validated in surgical patients at preoperative clinics. Combined with body mass index, age, neck size, and gender, it had a high sensitivity, especially for patients with moderate to severe OSA.