Evaluation of Dry Sensors for Neonatal EEG Recordings.
Evaluation of Dry Sensors for Neonatal EEG Recordings.
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DOI：
10.1097/wnp.0000000000000237
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发表时间：
2016-04
期刊：
影响因子：
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通讯作者：
Tsuchida TN
中科院分区：
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作者：
Fridman I;Cordeiro M;Rais-Bahrami K;McDonald NJ;Reese JJ Jr;Massaro AN;Conry JA;Chang T;Soussou W;Tsuchida TN
新生儿癫痫发作是新生儿重症监护室（NICU）中常见的神经病学诊断，在美国每年约有14，000名新生儿发生。虽然检测和治疗新生儿癫痫发作的唯一可靠方法是EEG记录，但许多新生儿没有EEG或在获得EEG时遇到延迟。获得新生儿EEG的障碍包括：1）缺乏熟练的EEG技术人员将常规湿电极应用于新生儿娇嫩的皮肤，2）由于皮肤准备不当和伪影导致的信号质量差，3）应用电极需要大量时间。干式传感器有可能克服这些障碍，但以前没有在新生儿身上进行过评估。对27例经后35-42.5周的新生儿进行了连续和同时的湿传感器和干传感器记录，持续1小时。记录的相关性和振幅进行了分析，并由神经生理学家审查。测试了干传感器在模拟胎脂上的性能。对干信号和湿信号的分析显示出良好的时域相关性（达到>0.8），给出了非叠加的传感器位置，以及相似的功率谱密度曲线。神经生理学家审查显示，在大多数临床相关EEG背景和癫痫发作模式方面，干和湿数据之间无统计学显著差异。在1小时的干燥传感器记录后，没有皮肤损伤。与湿电极相比，干传感器的阻抗和电伪影在很大程度上不受模拟胎脂的影响。本研究中评估的干式传感器有可能为新生儿提供高质量、及时的EEG记录，同时降低皮肤损伤风险。
Neonatal seizures are a common neurologic diagnosis in Neonatal Intensive Care Units (NICUs), occurring in approximately 14,000 newborns annually in the US. While the only reliable means of detecting and treating neonatal seizures is with an EEG recording, many neonates do not get an EEG or experience delays in getting them. Barriers to obtaining neonatal EEGs include: 1) lack of skilled EEG technologists to apply conventional wet electrodes to delicate neonatal skin, 2) poor signal quality due to improper skin preparation and artifact, 3) extensive time needed to apply electrodes. Dry sensors have the potential to overcome these obstacles but have not been previously evaluated on neonates. Sequential and simultaneous recordings with wet and dry sensors were performed for one hour on 27 neonates from 35-42.5 weeks postmenstrual age. Recordings were analyzed for correlation and amplitude, and were reviewed by neurophysiologists. Performance of dry sensors on simulated vernix was examined. Analysis of dry and wet signals showed good time-domain correlation (reaching >0.8) given the non-superimposed sensor positions, and similar power spectral density curves. Neurophysiologist reviews showed no statistically significant difference between dry and wet data on most clinically-relevant EEG background and seizure patterns. There was no skin injury after 1 hr of dry sensor recordings. In contrast to wet electrodes, impedance and electrical artifact of dry sensors were largely unaffected by simulated vernix. Dry sensors evaluated in this study have the potential to provide high-quality, timely EEG recordings on neonates with less risk of skin injury.