Seroprevalence and risk factors associated with Neospora caninum infection in different dog populations in Spain
Seroprevalence and risk factors associated with Neospora caninum infection in different dog populations in Spain
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DOI：
10.1016/j.vetpar.2007.12.005
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发表时间：
2008-03-25
影响因子：
2.6
通讯作者：
Ortega-Mora, L. M.
中科院分区：
文献类型：
--
作者：
Collantes-Fernandez, E.;Gomez-Bautista, A.;Ortega-Mora, L. M.
在这项研究中，对西班牙四个不同犬群的犬新孢子虫血清流行率和一些相关危险因素进行了调查。农场犬的犬新孢子虫血清阳性率显着较高 (51%, 51/100) (P < 0.001)，而家庭犬的犬新孢子虫血清阳性率则较低 (2.9%, 3/102) (P < 0.0001)。狩猎犬（23%，23/100）和流浪犬（24.5%，23/94）的血清阳性率中等，这两个群体之间没有观察到显着差异（P > 0.05）。滴度为 1:50-1:100（68%, 68/100）的狗数量显着高于滴度≥1:200（33%, 33/100）的狗（P < 0.0001）。与纯种狗相比，混合品种犬中更常检测到犬新孢子虫抗体（P < 0.01），但当按狗类型对数据进行分层时，未发现显着关联（P > 0.05）。在1岁以上的犬中观察到犬新孢子虫的患病率显着较高（P < 0.01），表明水平传播可能是最重要的感染途径。犬新孢子虫抗体的存在在婴儿利什曼原虫血清阳性狩猎（P < 0.05）和流浪狗（P < 0.00001）中显着更高。这项研究证实，在西班牙，农场犬、流浪犬和猎犬可被视为感染犬新孢子虫的高危犬群。 (C) 2007 Elsevier B.V. 保留所有权利。
In this study, Neospora caninum seroprevalence and some associated risk factors were investigated in four different dog populations in Spain. N. caninum seropositivity was significantly higher in farm dogs (51%, 51/100) (P < 0.001) and lower in household dogs (2.9%, 3/102) (P < 0.0001). The seroprevalence in hunting (23%, 23/100) and stray (24.5%, 23/94) dogs was moderate, and no significant differences were observed between these two populations (P > 0.05). A significantly higher number of dogs showed titres of 1:50-1:100(68%, 68/100) than >= 1:200 (33%, 33/100) titres (P < 0.0001). N. caninum antibodies were more often detected in mixed breed than pure breed dogs (P < 0.01), but when data were stratified by dog type a significant association was not found (P > 0.05). A significantly higher prevalence of N. caninum was observed in dogs over I year old (P < 0.01), indicating that horizontal transmission may be the most important route of infection. The presence of N. caninum antibodies was significantly more frequent in Leishmania infantum-seropositive hunting (P < 0.05) and stray dogs (P < 0.00001). This study confirms that farm, stray and hunting dogs can be considered at-risk dog populations for N. caninum infection in Spain. (C) 2007 Elsevier B.V. All rights reserved.