Masticatory muscle tendon-aponeurosis hyperplasia exhibits heterotopic calcification in tendons
Masticatory muscle tendon-aponeurosis hyperplasia exhibits heterotopic calcification in tendons
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DOI：
10.1111/odi.12140
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发表时间：
2014-05-01
期刊：
影响因子：
3.8
通讯作者：
Yoda, T.
中科院分区：
文献类型：
--
作者：
Sato, T.;Hori, N.;Yoda, T.
目的咀嚼肌腱腱膜增生症是一种与张口受限相关的新疾病。本研究通过电子显微镜和能量色散X射线分析分析咀嚼肌腱腱膜增生的肌肉和肌腱的显微结构特征，以确定元素成分。方法采用组织学分析检测钙化点。采用透射电子显微镜和扫描电子显微镜来阐明肌肉和肌腱的微观结构特征。采用能量色散X射线显微分析确定元素分布。结果与面部畸形相比，咀嚼肌腱腱膜增生的肌腱组织中可见矿化结节。电镜观察显示，与面部畸形组织相比，咀嚼肌腱腱膜增生的肌肉和肌腱组织出现退行性改变和独特的组织学表现。我们发现Ca、P和Si仅在咀嚼肌腱腱膜增生中检测到。结论我们证明咀嚼肌腱腱膜增生在肌腱组织中表现出异位钙化。
ObjectiveMasticatory muscle tendon-aponeurosis hyperplasia is a new disease entity associated with limited mouth opening. In this study, we analyzed the microstructural characteristics of muscles and tendons in masticatory muscle tendon-aponeurosis hyperplasia by electron microscopy and energy-dispersive X-ray analysis to determine the elemental composition.MethodsHistological analysis was performed to detect the calcification. Transmission electron microscopy and scanning electron microscopy were conducted to clarify the microstructural characteristics of muscles and tendons. Energy-dispersive X-ray microanalysis was performed to identify the distribution of elements.ResultsMineralized nodules were observed in tendon tissues of masticatory muscle tendon-aponeurosis hyperplasia as compared with facial deformity. Electron microscopy revealed that the muscle and tendon tissues in masticatory muscle tendon-aponeurosis hyperplasia showed degenerative changes and distinctive histological findings as compared with tissues in facial deformity. We found that Ca, P, and Si were detected only in masticatory muscle tendon-aponeurosis hyperplasia.ConclusionWe demonstrated that masticatory muscle tendon-aponeurosis hyperplasia exhibits heterotopic calcification in tendon tissues.